DMAP1 Antibody

Catalog Number:

47064

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NPF5
NCBI Gene ID:55929
Gene Accssion:EAX07050

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DMAP1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DMAP1 protein.

Applications:

WB, IHC

Background:

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 25-100

Datasheet PDF