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DDX50 Antibody

Catalog Number:

47041
other_names: GU2; GUB; mcdrh; RH-II/GuB

Amount:

100μg
calculated_mw: 83 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9BQ39
NCBI Gene ID:79009
Gene Accssion:BC000272

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human DDX50

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DDX50 protein.

Applications:

WB, IHC

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 25-100

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