DBT Antibody

Catalog Number:

47021

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P11182
NCBI Gene ID:1629
Gene Accssion:NP_001909

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DBT

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DBT protein.

Applications:

WB, IHC

Background:

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 20-100

Datasheet PDF