CYP3A5 Antibody

Catalog Number:

47007

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P20815
NCBI Gene ID:1577
Gene Accssion:NP_000768

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CYP3A5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYP3A5 protein.

Applications:

IHC

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.?

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF