CYP2C8 Antibody

Catalog Number:

47004

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P10632
NCBI Gene ID:1558
Gene Accssion:NP_000761

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CYP2C8

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYP2C8 protein.

Applications:

IHC

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.?

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF