CYB5R1 Antibody

Catalog Number:

46998

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UHQ9
NCBI Gene ID:51706
Gene Accssion:BC018732

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human CYB5R1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYB5R1 protein.

Applications:

WB, IHC

Background:

NADH-cytochrome b5 reductases participate in a variety of physiological processes including biosynthesis of cholesterol, methemoglobin reduction of erythrocytes, elongation of fatty acids and metabolism of drugs. CYB5R1 (cytochrome b5 reductase 1), also known as NADH-cytochrome b5 reductase 1, B5R1, NQO3A2, humb5R2 or NAD(P)H:quinone oxidoreductase type 3 polypeptide A2, is a 305 amino acid single-pass membrane protein that contains one FAD-binding FR-type domain and belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. Widely expressed, CYB5R1 binds FAD as a cofactor and is encoded by a gene located on human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 25-100

Datasheet PDF