CUTA Antibody

Catalog Number:

46995

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O60888
NCBI Gene ID:51596
Gene Accssion:BC005890

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human CUTA

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CUTA protein.

Applications:

IHC

Background:

CUTA, also known as ACHAP (acetylcholinesterase-associated protein), is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. Existing as multiple alternatively spliced isoforms, CUTA functions as a homotrimer that is thought to act as a component of an acetylcholinesterase (AChE)-attached complex, suggesting an involvement in AChE regulation. The gene encoding CUTA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinsons disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

References:

appl_detail:

Immunofluorescence:1: 40-200

Datasheet PDF