CTNND2 Antibody

Catalog Number:

46993

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UQB3
NCBI Gene ID:1501
Gene Accssion:NP_001323

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CTNND2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CTNND2 protein.

Applications:

IHC

Background:

This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF