COX4I2 Antibody

Catalog Number:

46975

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96KJ9
NCBI Gene ID:84701
Gene Accssion:NP_115998

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human COX4I2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total COX4I2 protein.

Applications:

IHC

Background:

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.

References:

appl_detail:

Immunofluorescence:1: 25-100

Datasheet PDF