COPS6 Antibody

Catalog Number:

46970

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q7L5N1
NCBI Gene ID:10980
Gene Accssion:BC002520

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total COPS6 protein.

Applications:

IHC

Background:

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.?

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF