CIRBP Antibody

Catalog Number:

46954

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q14011
NCBI Gene ID:1153
Gene Accssion:BC000403

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CIRBP protein.

Applications:

IHC

Background:

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF