CHERP Antibody

Catalog Number:

46951

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q8IWX8
NCBI Gene ID:10523
Gene Accssion:BC021294

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human CHERP

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CHERP protein.

Applications:

IHC

Background:

The regulation of the intracellular concentration of calcium is important for proper maintenance of voltage-gated ion channels which control muscle and nerve function. Calcium homeostasis is regulated by a variety of proteins. CHERP (calcium homeostasis endoplasmic reticulum protein), also known as SRA1, DAN16 or SCAF6, is a 916 amino acid protein that localizes to the cytoplasm and the endoplasmic reticulum (ER). Expressed in pancreas, brain, lung, placenta, liver, kidney, heart and skeletal muscle, CHERP is involved in maintaining calcium homeostasis and plays a role in cell growth and proliferation. CHERP contains one G-patch domain, one RPR domain and one SURP motif and is expressed as two isoforms due to alternative splicing events.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF