CELA3A Antibody

Catalog Number:

46948

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P09093
NCBI Gene ID:10136
Gene Accssion:BC008383

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human CELA3A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CELA3A protein.

Applications:

IHC

Background:

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF