CCNJ Antibody

Catalog Number:

46943

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q5T5M9
NCBI Gene ID:54619
Gene Accssion:NP_061957

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human CCNJ

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CCNJ protein.

Applications:

WB, IHC

Background:

Cyclin J is a 372 amino acid protein encoded by the human gene CCNJ located on chromosome 10. Cyclin J belongs to the cyclin family and contains one cyclin N-terminal domain. A cyclin forms a complex with its partner cyclin-dependent kinase (Cdk), which activates the protein kinase function of the Cdk. Cyclins are so named because their concentration varies in a cyclical fashion during the cell cycle. They are produced or degraded as needed in order to drive the cell through the different stages of the cell cycle. When its concentrations in the cell are low, the cyclin detaches from the Cdk, inhibiting the activity of the enzyme, probably by causing a protein chain to block the enzymatic site. Cyclin J-associated kinase activity is required for the early embryonic division cycles.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 20-100

Datasheet PDF