ALX4 Antibody

Catalog Number:

46928

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9H161
NCBI Gene ID:60529
Gene Accssion:NP_068745

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ALX4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ALX4 protein.

Applications:

WB

Background:

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

References:

appl_detail:

Western blotting:1:200-1000

Datasheet PDF