F5(Coagulation factor V light chain) Antibody

Catalog Number:

47757

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P12259
NCBI Gene ID:2153
Gene Accssion:NP_000121

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human F5(Coagulation factor V light chain)

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total F5(Coagulation factor V light chain) protein.

Applications:

IHC

Background:

This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.?

References:

appl_detail:

IHC dilution:1: 20-100

Datasheet PDF