ZBTB44 Antibody

Catalog Number:

46715

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8NCP5
NCBI Gene ID:29068
NCBI Protein:BC030580

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human ZBTB44

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ZBTB44 protein.

Applications:

IHC

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr¨¹ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 44 (ZBTB44), also known as BTBD15, is a 570 amino acid member of the Kr¨¹ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF