UCN3 Antibody

Catalog Number:

46694

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q969E3
NCBI Gene ID:114131
NCBI Protein:NP_444277

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human UCN3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UCN3 protein.

Applications:

WB IHC

Background:

This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 20-100

Datasheet PDF