SLC9A3R1 Antibody

Catalog Number:

46674

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O14745
NCBI Gene ID:9368
NCBI Protein:NP_004243

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human SLC9A3R1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC9A3R1 protein.

Applications:

IHC

Background:

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF