SHPK Antibody

Catalog Number:

46666

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UHJ6
NCBI Gene ID:23729
NCBI Protein:BC020543

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human SHPK

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SHPK protein.

Applications:

WB IHC

Background:

The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 40-200

Datasheet PDF