REST Antibody

Catalog Number:

46657

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q13127
NCBI Gene ID:5978
NCBI Protein:NP_005603

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human REST

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total REST protein.

Applications:

IHC

Background:

This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF