USP14 Antibody

Catalog Number:

46697

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P54578
NCBI Gene ID:9097
NCBI Protein:BC003556

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human USP14

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total USP14 protein.

Applications:

WB

Background:

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF