PRPF8 Antibody

Catalog Number:

46649

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q6P2Q9
NCBI Gene ID:10594
NCBI Protein:NP_006436

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human PRPF8

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PRPF8 protein.

Applications:

WB IHC

Background:

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 20-100

Datasheet PDF