PMP22 Antibody

Catalog Number:

46642

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q01453
NCBI Gene ID:5376
NCBI Protein:NP_000295

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human PMP22

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PMP22 protein.

Applications:

WB IHC

Background:

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 20-100

Datasheet PDF