NRG2 Antibody

Catalog Number:

46631

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O14511
NCBI Gene ID:9542
NCBI Protein:NP_001171864

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human NRG2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total NRG2 protein.

Applications:

IHC

Background:

This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.?

References:

appl_detail:

Immunohistochemistry: 1: 50-300

Datasheet PDF