NDUFB11 Antibody

Catalog Number:

46624

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NX14
NCBI Gene ID:54539
NCBI Protein:BC010665

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human NDUFB11

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total NDUFB11 protein.

Applications:

WB IHC

Background:

Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1: 50-300

Datasheet PDF