MST1R Antibody

Catalog Number:

46615

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q04912
NCBI Gene ID:4486
NCBI Protein:NP_001231866

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human MST1R

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MST1R protein.

Applications:

IHC

Background:

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF