MICU1 Antibody

Catalog Number:

46612

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9BPX6
NCBI Gene ID:10367
NCBI Protein:BC004190

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human MICU1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MICU1 protein.

Applications:

WB IHC

Background:

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 25-100

Datasheet PDF