LRRC16A Antibody

Catalog Number:

46601

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5VZK9
NCBI Gene ID:55604
NCBI Protein:NP_060110

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human LRRC16A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total LRRC16A protein.

Applications:

IHC

Background:

Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF