KLHL36 Antibody

Catalog Number:

46593

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8N4N3
NCBI Gene ID:79786
NCBI Protein:NP_079007

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human KLHL36

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total KLHL36 protein.

Applications:

WB

Background:

C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF