HOXD8 Antibody

Catalog Number:

46580

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P13378
NCBI Gene ID:3234
NCBI Protein:NP_062458

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human HOXD8

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HOXD8 protein.

Applications:

IHC

Background:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF