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HGH1 Antibody

Catalog Number:

46573
other_names: BRP16; BRP16L; FAM203A; FAM203B; C8orf30A; C8orf30B

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9BTY7
NCBI Gene ID:51236
NCBI Protein:NP_057542

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human HGH1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total HGH1 protein.

Applications:

IHC

Background:

HGH1, is also known as BRP16, Brp16 is a 256 amino acid protein encoded by a gene on human chromosome 8. Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

References:

appl_detail:


Immunohistochemistry: 1: 30-150

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