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GRM5 Antibody

Catalog Number:

46569
other_names: mGlu5; GPRC1E; MGLUR5; PPP1R86

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:P41594
NCBI Gene ID:2915
NCBI Protein:NP_000833

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human GRM5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total GRM5 protein.

Applications:

IHC

Background:

This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

References:

appl_detail:


Immunohistochemistry: 1: 25-100

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