GRIA4 Antibody

Catalog Number:

46568

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P48058
NCBI Gene ID:2893
NCBI Protein:NP_000820

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human GRIA4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total GRIA4 protein.

Applications:

IHC

Background:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF