F2RL1 Antibody

Catalog Number:

46560

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P55085
NCBI Gene ID:2150
NCBI Protein:NP_005233

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human F2RL1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total F2RL1 protein.

Applications:

IHC

Background:

Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.?

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF