EMC10 Antibody

Catalog Number:

46558

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5UCC4
NCBI Gene ID:284361
NCBI Protein:NP_996261

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human EMC10

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total EMC10 protein.

Applications:

WB IHC

Background:

EMC10, also known as C19orf63, C19orf63 is a 262 amino acid protein that exists as two alternatively isoforms and are encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 30-150

Datasheet PDF