COPS8 Antibody

Catalog Number:

46535

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q99627
NCBI Gene ID:10920
NCBI Protein:BC003090

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human COPS8

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total COPS8 protein.

Applications:

IHC

Background:

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF