COL9A1 Antibody

Catalog Number:

46534

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P20849
NCBI Gene ID:1297
NCBI Protein:BC015409

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the N terminal of human COL9A1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total COL9A1 protein.

Applications:

IHC

Background:

This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.?

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF