CNTNAP1 Antibody

Catalog Number:

46528

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P78357
NCBI Gene ID:8506
NCBI Protein:NP_003623

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CNTNAP1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CNTNAP1 protein.

Applications:

WB IHC

Background:

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 20-100

Datasheet PDF