CLSTN1 Antibody

Catalog Number:

46519

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O94985
NCBI Gene ID:22883
NCBI Protein:NP_001009566

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CLSTN1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CLSTN1 protein.

Applications:

IHC

Background:

This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1: 10-50

Datasheet PDF