CLPX Antibody

Catalog Number:

46518

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O76031
NCBI Gene ID:10845
NCBI Protein:NP_006651

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CLPX

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CLPX protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 20-100

Datasheet PDF