CITED4 Antibody

Catalog Number:

46506

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96RK1
NCBI Gene ID:163732
NCBI Protein:NP_597724

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human CITED4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CITED4 protein.

Applications:

IHC

Background:

The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors.?

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF