CFL2 Antibody

Catalog Number:

46483

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9Y281
NCBI Gene ID:1073
NCBI Protein:NP_068733

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CFL2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CFL2 protein.

Applications:

WB IHC

Background:

This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 20-100

Datasheet PDF