CETN3 Antibody

Catalog Number:

46481

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O15182
NCBI Gene ID:1070
NCBI Protein:BC005383

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human CETN3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CETN3 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 30-150

Datasheet PDF