CDKL4 Antibody

Catalog Number:

46456

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5MAI5
NCBI Gene ID:344387
NCBI Protein:NP_001009565

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human CDKL4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDKL4 protein.

Applications:

WB IHC

Background:

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 30-150

Datasheet PDF