CDC42BPA Antibody

Catalog Number:

46443

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5VT25
NCBI Gene ID:8476
NCBI Protein:XP_005273381

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CDC42BPA

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDC42BPA protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 30-150

Datasheet PDF