CDC14B Antibody

Catalog Number:

46441

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O60729
NCBI Gene ID:8555
NCBI Protein:NP_201588

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CDC14B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDC14B protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF