CDC14A Antibody

Catalog Number:

46440

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UNH5
NCBI Gene ID:8556
NCBI Protein:NP_003663

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CDC14A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDC14A protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.?

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF