CD8A Antibody

Catalog Number:

46438

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P01732
NCBI Gene ID:925
NCBI Protein:NP_001759

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CD8A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CD8A protein.

Applications:

WB IHC

Background:

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 30-150

Datasheet PDF