IGFBP2 Antibody

Catalog Number:

46587

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P18065
NCBI Gene ID:3485
NCBI Protein:NP_000588

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human IGFBP2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total IGFBP2 protein.

Applications:

IHC

Background:

The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF